Upcoming Events

March 29, 2025
Bike MS: Suncoast Challenge 2025
Lakewood Ranch, Florida

Experience the thrill of Bike MS: Suncoast Challenge, a one-day cycling adventure just an hour from Tampa. Pedal through the scenic landscapes of Sarasota County, with coastal views along Casey Key, breathtaking bridges, and the renowned 5-star Legacy Cycling Trail — you may even encounter a pirate or two along the way.

The excitement kicks off and wraps up on Main Street at Lakewood Ranch, where we’ll celebrate with an epic pirate-themed street party for all participants. Feel the extraordinary support and excitement throughout your journey as we come together to reach our goal — a world free of MS.

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April 5-6, 2025
Bike MS: Dat's How We Roll 2025
Hammond, Louisiana

Get ready for the Ride of a Lifetime

Bike MS is one of the largest fundraising cycling series in the world. With dedicated riders like you, we are working to end multiple sclerosis forever, one pedal stroke at a time. Feel the extraordinary support and excitement throughout your journey as we come together to reach our goal—a world free of MS.|

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April 5-6, 2025
Bike MS: Breakaway to the Palm Beaches 2025
Boca Raton, Florida 

Join a community of riders dedicated to changing the world for people with MS at Bike MS: Breakaway to the Palm Beaches in Boca Raton, Florida.

 Cyclists will start and finish at the Boca Raton Innovation Campus and head north on A1A through the Palm Beaches on day one, and travel south on day two. With routes ranging from 25 to 95 miles, this ride is perfect for both experienced and novice riders.  

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April 9-13, 2025
Best Buddies Challenge: California 2025
Palo Alto, California

We are combining our two signature cycling events, the Best Buddies Challenge: California, and the Best Buddies Breakaway Camp: Palo Alto with the launch of the “Queen Stage.”

Join us on April 12, 2025, for the Queen Stage of the Best Buddies Breakaway Camp: Palo Alto! 

Get ready for an unforgettable cycling adventure and VIP experience at our inaugural Queen Stage event on Friday, April 11, and Saturday, April 12, 2025!Kick off the weekend with an exclusive VIP dinner on Friday evening, where you’ll mingle with fellow cycling enthusiasts and legendary pro-cyclists like Alberto Contador, Andrew Talansky and Cam Wurf. Enjoy a luxurious one-night stay at the stunning Rosewood Hotel in Menlo Park, complete with access to all hotel amenities.On Saturday, embark on an exhilarating ride tailored to cyclists of all abilities. Choose between the challenging 70-mile route, leading you through picturesque roads to the breathtaking Skyline Ridge and culminating in the iconic Tunitas Climb, or the scenic 43-mile route, showcasing the beauty of La Honda Creek Preserve and finishing on Tunitas. Both routes are fully supported, featuring rest stops every 25 miles and dependable support vehicles to ensure a fantastic experience for every rider.Celebrate your achievement at a delightful post-event luncheon, rounding out a weekend filled with camaraderie, comfort, and cycling passion. Don’t miss this extraordinary event—challenge yourself, connect with fellow riders, and create lasting memories!

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May 3, 2025
Roanoke Roundup Festival 2025
Roanoke, Texas

Roanoke Roundup is the biggest charity event of the year, benefiting the Guns & Hoses Foundation of North Texas and Speedway Children’s Charities. This event is a free family fun day filled with the annual steak cook-off competition, eating competitions, BBQ tasting, live music, children's activities, and more. Save the date for Saturday, May 3rd, 2025!

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May 17-18, 2025
Bike MS: Los Angeles Coastal Challenge 2025
Los Angeles, California

Bike MS: Los Angeles Coastal Challenge is a two-day ride with routes along the Southern California coastline. Cycle along iconic beaches towards the surfing paradise of Rincon Point. The routes throughout the weekend are fit for beginner, intermediate and advanced riders. Options will range from Saturday’s 30-mile route that offers flat, scenic vistas, to our Sunday routes that include a perfect view of the Ventura coastline. Not only that, but you’ll also have access to the Ojai River Valley Bikeway, one of the most beautiful class one bike paths in Southern California.

This year we will also have an all-new kids’ zone, along with great food and entertainment. We will once again offer our typical options to join our charter bus or grab Metrolink train tickets. Feel the extraordinary support and excitement throughout your journey as we come together to reach our goal— a world free of MS. You're not going to want to miss this amazing ride.

Route distances:
Day 1 - 100, 60 mile rides starting in Santa Monica and a 30 mile ride starting in Ventura.
All rides finish in Ventura.
Day 2 - 50 and 30 mile rides both starting and ending in Ventura.

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May 31, 2025
Best Buddies Challenge Hyannis Port
North Quincy, Massachusetts 

Join us on Saturday, May 31, 2025, and choose to ride 100, 55, or 20 miles with cyclists of all abilities including celebrities, pro-cyclists Alberto Contador, Cam Wurf, and others. Each route takes riders along scenic, country roads to the beach in Hyannis Port. All rides are fully supported, with rest stops every 25 miles and support vehicles on the road.

Each route takes riders along scenic, country roads to the beach in Hyannis Port. All rides are fully supported, with rest stops every 25 miles and support vehicles on the road.
There’s nothing like a Best Buddies Challenge. Find out for yourself. Sign up as an individual or form a team with friends and together we will help Best Buddies enhance the lives of people with intellectual and developmental disabilities.

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June 28-29, 2025
Bike MS: Cape Cod Getaway 2025
Quincy, Massachusetts 

Join the largest Bike MS event in the New England area and celebrate 41 years of Bike MS: Cape Cod Getaway! Take in beautiful Cape Cod views as you ride from Quincy to Provincetown, MA, including crossing the Bourne Bridge traffic-free, on this two-day cycling experience.

You can choose from multiple route options over the weekend, including our new “Leap Ahead Route” where you can skip closer to the finish line. On day one, we’ll celebrate at the finish with music, recovery stations, and a lot of food and drinks. On day two, you'll head out to some more amazing landscapes and make your way to the final finish line in Ptown, with everyone's favorite ferry ride back to Quincy to end an amazing weekend!

Can’t join the full weekend? Ride one day with transportation available back on Saturday. 

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July 4, 2025
Independence Fest 2025
Flower Mound, Texas

Every 4^th of July, join us at Flower Mound’s biggest celebration of the year! Independence Fest features a Children’s Parade, live music, a variety of food trucks and vendors, a kid’s zone, car show, and, of course, an explosive fireworks finale! Past musical acts have included Josh Abbott Band, Bret Michaels, Pat Green, Brothers Osborne, Eli Young Band, and many more.

This year, both the Children’s Parade and Independence Fest 2025 will be held on Friday, July 4. As the event gets closer, this page will be updated with festival details, as well as information on vendor registration and sponsorship opportunities.

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July 4, 2025
Bedford 4thFest
Bedford, Texas

Bedford 4thFest is the City of Bedford's annual Fourth of July celebration at Generations Park at Boys Ranch. The day features free live music, a kid’s zone, food trucks, and a spectacular fireworks show when the sun goes down. 

Additional details on Bedford 4thFest in 2025 will be shared in the spring.


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September 13, 2025
Bike MS: Georgia Peach Ride 2025
LaGrange, GA 

Embrace the extraordinary! Our ride will have incredible scenery with route options ranging from 22 to 100 miles. Enjoy this agritourism-centric ride as you travel across lakes, mountains and the beautiful Georgia countryside. Cross the finish line at Wild Leap Brew Co. where you’ll be greeted with drinks, music and farm-to-table dining. Pedal towards a world free of MS with Bike MS: Georgia Peach Ride.



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September 27-28, 2025
Bike MS: Waves To Wine 2025
San Francisco, CA

Your ride is going to be golden. With plenty of routes to choose from, you’ll have the chance to journey from downtown San Francisco to the heart of wine country or take a ride through coastal forests. If you choose the 72- or 102-mile route, you’ll get to pass over the Golden Gate Bridge! Our other routes start and end in wine country, so no matter what you choose, you know it’ll be an amazing time. Experience 40 years of Bike MS: Waves to Wine and take in the best of California.

A community of riders dedicated to changing the world for people with MS one pedal stroke at a time. Feel the extraordinary support and excitement throughout your journey as we come together to reach our goal—a world free of MS.

Details for this ride are not available at this time.



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October 4, 2025
Best Buddies Challenge: New York

Choose to ride 100, 40 or 15-miles

Riders will embark from Central Park and cross the George Washington Bridge to continue north along the Hudson River Valley to Bear Mountain State Park. From the summit, riders will roll through Harriman State Park and continue west to finish at the Glenmere Mansion in the Ramapo Mountains.

All routes are all well marked and fully supported. Rest stops along the ride routes feature energy food and drinks, bathrooms, and mechanical and medical assistance. As part of the five-star experience, all rides are assisted by support vehicles and law enforcement officers once underway. We also have sweep vans, ride officials and course marshals that make sure no participant is left behind.

All funds raised benefit Best Buddies International, the largest organization dedicated to ending the social, physical and economic isolation of the 200 million people worldwide with intellectual and developmental disabilities (IDD). Our programs empower people with IDD to form meaningful friendships with their peers, secure jobs, improve communication and advocacy skills, and live independently, while also offering support for their families.

The IDD community that Best Buddies serves individuals with IDD and their families. The IDD community includes, but is not limited to, people with Down syndrome, autism, Fragile X, Williams syndrome, and other undiagnosed disabilities.

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October 4 & 5, 2025
Bike MS: PGA Cycle to the Shore
Ponte Vedra Beach, Florida

Enjoy this two-day cycling event with amazing coastal views. On day one, you can choose your start line location at either TPC Sawgrass or Marineland and then make your way to Daytona Beach where you’ll have an amazing beachside celebration with your fellow cyclists. The following morning, you’ll finish the weekend by making your way back to your day one start location. Experience the extraordinary journey as we come together to reach our goal — a world free of MS.
Details for this ride are not available at this time.

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October 11, 2025
Celebrate Roanoke Festival
Roanoke, Texas

Mark your calendars for the 28th annual Celebrate Roanoke Street Festival on Saturday, October 11th, 2025. This event will feature several blocks of entertainment including children's activities, Western entertainment, performances on multiple stages, and more!

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November 15, 2025
Best Buddies Challenge: Miami 2025
Miami, Florida

Join cycling legend Chris Froome on Saturday, November 16, 2024 for a 80-mile ride! Starting and finishing at the W South Beach. Riders will be escorted and followed in a closed peloton by police vehicles at a minimum 18 mph pace. If equipment fails the ride does not stop. Our SAG support, provided by Mack Cycle and Fitness, will either provide an alternative top of the line bike and/or make the necessary repair to allow members to rejoin the peloton.

Featuring two fully stocked rest stops, waterfront views, and a ride through some of the most historic and scenic locations in Miami, South Beach and Key Biscayne. 

Once riders return to the finish line, they will be greeted with refreshments, hot showers, professional massages, and lunch. Later in the evening, riders will attend the Best Buddies Miami Gala.

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